Creatinine Clearance (CrCl) & GFR Calculator
Enter age, weight, sex and serum creatinine to get Cockcroft-Gault CrCl for drug dosing plus CKD-EPI 2021 eGFR with instant CKD staging.
Patient Details
Disclaimer: Estimates only. Cockcroft-Gault and CKD-EPI are unreliable in acute kidney injury, extremes of body weight, pregnancy and amputees. Always confirm with clinical judgement before adjusting doses.
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How creatinine clearance is calculated
The Cockcroft-Gault formula estimates creatinine clearance as ((140 − age) × weight kg) / (72 × serum creatinine mg/dL), multiplied by 0.85 for females. It remains the standard for renal drug dose adjustment because most drug labels were written against it. The CKD-EPI 2021 equation gives eGFR normalised to 1.73 m² and is used to stage chronic kidney disease.
CKD staging by eGFR
- → G1 ≥ 90 — Normal or high
- → G2 60–89 — Mildly decreased
- → G3a 45–59 — Mild to moderately decreased
- → G3b 30–44 — Moderately to severely decreased
- → G4 15–29 — Severely decreased
- → G5 < 15 — Kidney failure
Frequently Asked Questions
What is a normal creatinine clearance?
Approximately 90–140 mL/min in men and 80–125 mL/min in women, falling gradually with age.
Why does my CrCl differ from eGFR?
CrCl is absolute (mL/min) and weight-dependent; eGFR is body-surface-area normalised. Use CrCl for dosing, eGFR for CKD staging.
Which weight should I use?
Actual body weight for normal BMI, ideal body weight when overweight, and adjusted body weight in obesity. Enter height to see the ideal-body-weight value too.
Related Free Tools
- → BMI & BSA Calculator
- → Pediatric Dose Calculator
- → Glasgow Coma Scale (GCS) Calculator
- → Prescription PDF Generator
Reference: KDIGO 2024 CKD guideline and the NKF CKD-EPI 2021 creatinine equation — National Kidney Foundation.